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Mometasone Furoate Suppresses PMA-Induced MUC-5AC and MUC-2 Production in Human Airway Epithelial Cells

BACKGROUND: Mucus hypersecretion from airway epithelium is a characteristic feature of airway inflammatory diseases. Tumor necrosis factor α (TNF-α) regulates mucin synthesis. Glucocorticoids including mometasone fuorate (MF) have been used to attenuate airway inflammation. However, effects of MF on...

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Detalles Bibliográficos
Autores principales: Poachanukoon, Orapan, Koontongkaew, Sittichai, Monthanapisut, Paopanga, Pattanacharoenchai, Napaporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Tuberculosis and Respiratory Diseases 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256341/
https://www.ncbi.nlm.nih.gov/pubmed/28119748
http://dx.doi.org/10.4046/trd.2017.80.1.60