Superior Multiplexing Capacity of PlexPrimers Enables Sensitive and Specific Detection of SNPs and Clustered Mutations in qPCR

BACKGROUND: Whilst qPCR provides an extremely powerful tool for genetic analysis, some applications such as multiplexing variant alleles (eg SNPs, point mutations or deletions), remain challenging using current primer/probe systems. The novel design features of PlexPrimers allow sensitive, multiplex...

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Detalles Bibliográficos
Autores principales: Tan, Lit Yeen, Walker, Samantha Michelle, Lonergan, Tina, Lima, Nicole Elizabeth, Todd, Alison Velyian, Mokany, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256879/
https://www.ncbi.nlm.nih.gov/pubmed/28114309
http://dx.doi.org/10.1371/journal.pone.0170087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256879/
https://www.ncbi.nlm.nih.gov/pubmed/28114309
http://dx.doi.org/10.1371/journal.pone.0170087

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