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Low Expression in Xenopus Oocytes and Unusual Functional Properties of α(1)β(2)γ(2) GABA(A) Receptors with Non-Conventional Subunit Arrangement
The major subunit isoform of GABA(A) receptors is α(1)β(2)γ(2). The subunits are thought to surround an ion pore with the counterclockwise arrangement α(1)γ(2)β(2)α(1)β(2) as seen from the outside of the neuron. These receptors have two agonist sites and one high affinity drug binding site specific...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256883/ https://www.ncbi.nlm.nih.gov/pubmed/28114407 http://dx.doi.org/10.1371/journal.pone.0170572 |