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Hepatitis C Virus Induces MDSCs-Like Monocytes through TLR2/PI3K/AKT/STAT3 Signaling

BACKGROUND AND AIMS: Recent studies reveal the accumulation of myeloid derived suppressor cells (MDSCs) in human peripheral blood mononuclear cells (PBMCs) following HCV infection, which may facilitate and maintain HCV persistent infection. The mechanisms by which HCV induces MDSCs are poorly unders...

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Detalles Bibliográficos
Autores principales: Zhai, Naicui, Li, Haijun, Song, Hongxiao, Yang, Yang, Cui, An, Li, Tianyang, Niu, Junqi, Crispe, Ian Nicholas, Su, Lishan, Tu, Zhengkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256909/
https://www.ncbi.nlm.nih.gov/pubmed/28114346
http://dx.doi.org/10.1371/journal.pone.0170516