TSA and BIX-01294 Induced Normal DNA and Histone Methylation and Increased Protein Expression in Porcine Somatic Cell Nuclear Transfer Embryos

The poor efficiency of animal cloning is mainly attributed to the defects in epigenetic reprogramming of donor cells’ chromatins during early embryonic development. Previous studies indicated that inhibition of histone deacetylases or methyltransferase, such as G9A, using Trichostatin A (TSA) or BIX...

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Detalles Bibliográficos
Autores principales: Cao, Zubing, Hong, Renyun, Ding, Biao, Zuo, Xiaoyuan, Li, Hui, Ding, Jianping, Li, Yunsheng, Huang, Weiping, Zhang, Yunhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256949/
https://www.ncbi.nlm.nih.gov/pubmed/28114389
http://dx.doi.org/10.1371/journal.pone.0169092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256949/
https://www.ncbi.nlm.nih.gov/pubmed/28114389
http://dx.doi.org/10.1371/journal.pone.0169092

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