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RhoGTPase Regulators Orchestrate Distinct Stages of Synaptic Development

Small RhoGTPases regulate changes in post-synaptic spine morphology and density that support learning and memory. They are also major targets of synaptic disorders, including Autism. Here we sought to determine whether upstream RhoGTPase regulators, including GEFs, GAPs, and GDIs, sculpt specific st...

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Detalles Bibliográficos
Autores principales: Martin-Vilchez, Samuel, Whitmore, Leanna, Asmussen, Hannelore, Zareno, Jessica, Horwitz, Rick, Newell-Litwa, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256999/
https://www.ncbi.nlm.nih.gov/pubmed/28114311
http://dx.doi.org/10.1371/journal.pone.0170464