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Using Chemical Reaction Kinetics to Predict Optimal Antibiotic Treatment Strategies

Identifying optimal dosing of antibiotics has proven challenging—some antibiotics are most effective when they are administered periodically at high doses, while others work best when minimizing concentration fluctuations. Mechanistic explanations for why antibiotics differ in their optimal dosing a...

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Detalles Bibliográficos
Autores principales: Abel zur Wiesch, Pia, Clarelli, Fabrizio, Cohen, Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257006/
https://www.ncbi.nlm.nih.gov/pubmed/28060813
http://dx.doi.org/10.1371/journal.pcbi.1005321