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Using Chemical Reaction Kinetics to Predict Optimal Antibiotic Treatment Strategies
Identifying optimal dosing of antibiotics has proven challenging—some antibiotics are most effective when they are administered periodically at high doses, while others work best when minimizing concentration fluctuations. Mechanistic explanations for why antibiotics differ in their optimal dosing a...
Autores principales: | Abel zur Wiesch, Pia, Clarelli, Fabrizio, Cohen, Ted |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257006/ https://www.ncbi.nlm.nih.gov/pubmed/28060813 http://dx.doi.org/10.1371/journal.pcbi.1005321 |
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