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Investigating Structure and Dynamics of Proteins in Amorphous Phases Using Neutron Scattering

In order to increase shelf life and minimize aggregation during storage, many biotherapeutic drugs are formulated and stored as either frozen solutions or lyophilized powders. However, characterizing amorphous solids can be challenging with the commonly available set of biophysical measurements used...

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Detalles Bibliográficos
Autores principales: Castellanos, Maria Monica, McAuley, Arnold, Curtis, Joseph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257034/
https://www.ncbi.nlm.nih.gov/pubmed/28138368
http://dx.doi.org/10.1016/j.csbj.2016.12.004