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Investigating Structure and Dynamics of Proteins in Amorphous Phases Using Neutron Scattering
In order to increase shelf life and minimize aggregation during storage, many biotherapeutic drugs are formulated and stored as either frozen solutions or lyophilized powders. However, characterizing amorphous solids can be challenging with the commonly available set of biophysical measurements used...
Autores principales: | Castellanos, Maria Monica, McAuley, Arnold, Curtis, Joseph E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257034/ https://www.ncbi.nlm.nih.gov/pubmed/28138368 http://dx.doi.org/10.1016/j.csbj.2016.12.004 |
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