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IL-4-producing ILC2s are required for the differentiation of T(H)2 cells following Heligmosomoides polygyrus infection

Immunity to many human and murine gastrointestinal helminth parasites requires interleukin-4 (IL-4)-directed type 2 helper (T(H)2) differentiation of CD4(+) T cells to elicit type-2 immunity. Despite a good understanding of the inflammatory cascade elicited following helminth infection, the initial...

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Detalles Bibliográficos
Autores principales: Pelly, VS, Kannan, Y, Coomes, SM, Entwistle, LJ, Rückerl, D, Seddon, B, MacDonald, AS, McKenzie, A, Wilson, MS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257265/
https://www.ncbi.nlm.nih.gov/pubmed/26883724
http://dx.doi.org/10.1038/mi.2016.4