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IL-4-producing ILC2s are required for the differentiation of T(H)2 cells following Heligmosomoides polygyrus infection
Immunity to many human and murine gastrointestinal helminth parasites requires interleukin-4 (IL-4)-directed type 2 helper (T(H)2) differentiation of CD4(+) T cells to elicit type-2 immunity. Despite a good understanding of the inflammatory cascade elicited following helminth infection, the initial...
Autores principales: | Pelly, VS, Kannan, Y, Coomes, SM, Entwistle, LJ, Rückerl, D, Seddon, B, MacDonald, AS, McKenzie, A, Wilson, MS |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5257265/ https://www.ncbi.nlm.nih.gov/pubmed/26883724 http://dx.doi.org/10.1038/mi.2016.4 |
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