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Maternal blood lead concentrations, DNA methylation of MEG3 DMR regulating the DLK1/MEG3 imprinted domain and early growth in a multiethnic cohort

Prenatal exposure to lead (Pb) is known to decrease fetal growth; but its effects on postnatal growth and mechanistic insights linking Pb to growth are not clearly defined. Genomically imprinted genes are powerful regulators of growth and energy utilization, and may be particularly vulnerable to env...

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Detalles Bibliográficos
Autores principales: Nye, Monica D., King, Katherine E., Darrah, Thomas H., Maguire, Rachel, Jima, Dereje D., Huang, Zhiqing, Mendez, Michelle A., Fry, Rebecca C., Jirtle, Randy L., Murphy, Susan K., Hoyo, Cathrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258134/
https://www.ncbi.nlm.nih.gov/pubmed/28123784
http://dx.doi.org/10.1093/eep/dvv009