Glucose Driven Changes in Beta Cell Identity Are Important for Function and Possibly Autoimmune Vulnerability during the Progression of Type 1 Diabetes

This commentary explores the hypothesis that when autoimmunity leads to a fall of beta cell mass during the progression of type 1 diabetes (T1D), rising glucose levels cause major changes in beta cell identity. This then leads to profound changes in secretory function and less well-understood change...

Descripción completa

Detalles Bibliográficos
Autores principales: Weir, Gordon C., Bonner-Weir, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258704/
https://www.ncbi.nlm.nih.gov/pubmed/28174593
http://dx.doi.org/10.3389/fgene.2017.00002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258704/
https://www.ncbi.nlm.nih.gov/pubmed/28174593
http://dx.doi.org/10.3389/fgene.2017.00002

Ejemplares similares