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P2X Receptors Inhibit NaCl Absorption in mTAL Independently of Nitric Oxide

Activation of basolateral P2X receptors markedly reduces NaCl absorption in mouse medullary thick ascending limb (mTAL). Here we tested the role of nitric oxide (NO) in the ATP-mediated (P2X) transport inhibition. We used isolated, perfused mTALs from mice to electrically measure NaCl absorption. By...

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Detalles Bibliográficos
Autores principales: Svendsen, Samuel L., Isidor, Søren, Praetorius, Helle A., Leipziger, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258741/
https://www.ncbi.nlm.nih.gov/pubmed/28174542
http://dx.doi.org/10.3389/fphys.2017.00018