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Reduced paucimannosidic N‐glycan formation by suppression of a specific β‐hexosaminidase from Nicotiana benthamiana

Plants are attractive hosts for the production of recombinant glycoproteins for therapeutic use. Recent advances in glyco‐engineering facilitate the elimination of nonmammalian‐type glycosylation and introduction of missing pathways for customized N‐glycan formation. However, some therapeutically re...

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Detalles Bibliográficos
Autores principales: Shin, Yun‐Ji, Castilho, Alexandra, Dicker, Martina, Sádio, Flavio, Vavra, Ulrike, Grünwald‐Gruber, Clemens, Kwon, Tae‐Ho, Altmann, Friedrich, Steinkellner, Herta, Strasser, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259580/
https://www.ncbi.nlm.nih.gov/pubmed/27421111
http://dx.doi.org/10.1111/pbi.12602