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Reduced paucimannosidic N‐glycan formation by suppression of a specific β‐hexosaminidase from Nicotiana benthamiana
Plants are attractive hosts for the production of recombinant glycoproteins for therapeutic use. Recent advances in glyco‐engineering facilitate the elimination of nonmammalian‐type glycosylation and introduction of missing pathways for customized N‐glycan formation. However, some therapeutically re...
Autores principales: | Shin, Yun‐Ji, Castilho, Alexandra, Dicker, Martina, Sádio, Flavio, Vavra, Ulrike, Grünwald‐Gruber, Clemens, Kwon, Tae‐Ho, Altmann, Friedrich, Steinkellner, Herta, Strasser, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259580/ https://www.ncbi.nlm.nih.gov/pubmed/27421111 http://dx.doi.org/10.1111/pbi.12602 |
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