Membrane Perturbation of ADP-insensitive Phosphoenzyme of Ca(2+)-ATPase Modifies Gathering of Transmembrane Helix M2 with Cytoplasmic Domains and Luminal Gating

Ca(2+) transport by sarcoplasmic reticulum Ca(2+)-ATPase involves ATP-dependent phosphorylation of a catalytic aspartic acid residue. The key process, luminal Ca(2+) release occurs upon phosphoenzyme isomerization, abbreviated as E1PCa(2) (reactive to ADP regenerating ATP and with two occluded Ca(2+...

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Detalles Bibliográficos
Autores principales: Danko, Stefania, Yamasaki, Kazuo, Daiho, Takashi, Suzuki, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259720/
https://www.ncbi.nlm.nih.gov/pubmed/28117348
http://dx.doi.org/10.1038/srep41172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259720/
https://www.ncbi.nlm.nih.gov/pubmed/28117348
http://dx.doi.org/10.1038/srep41172

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