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Membrane Perturbation of ADP-insensitive Phosphoenzyme of Ca(2+)-ATPase Modifies Gathering of Transmembrane Helix M2 with Cytoplasmic Domains and Luminal Gating
Ca(2+) transport by sarcoplasmic reticulum Ca(2+)-ATPase involves ATP-dependent phosphorylation of a catalytic aspartic acid residue. The key process, luminal Ca(2+) release occurs upon phosphoenzyme isomerization, abbreviated as E1PCa(2) (reactive to ADP regenerating ATP and with two occluded Ca(2+...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259720/ https://www.ncbi.nlm.nih.gov/pubmed/28117348 http://dx.doi.org/10.1038/srep41172 |