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Identification of Key Residues for Urate Specific Transport in Human Glucose Transporter 9 (hSLC2A9)

Human glucose transporter 9 (hSLC2A9) is critical in human urate homeostasis, for which very small deviations can lead to chronic or acute metabolic disorders. Human SLC2A9 is unique in that it transports hexoses as well as the organic anion, urate. This ability is in contrast to other homologous su...

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Detalles Bibliográficos
Autores principales: Long, Wentong, Panigrahi, Rashmi, Panwar, Pankaj, Wong, Kenneth, O′Neill, Debbie, Chen, Xing-Zhen, Lemieux, M. Joanne, Cheeseman, Chris I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259734/
https://www.ncbi.nlm.nih.gov/pubmed/28117388
http://dx.doi.org/10.1038/srep41167