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The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels

Rer1 is a sorting receptor in the early secretory pathway that controls the assembly and the cell surface transport of selected multimeric membrane protein complexes. Mice with a Purkinje cell (PC) specific deletion of Rer1 showed normal polarization and differentiation of PCs and normal development...

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Detalles Bibliográficos
Autores principales: Valkova, Christina, Liebmann, Lutz, Krämer, Andreas, Hübner, Christian A., Kaether, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259745/
https://www.ncbi.nlm.nih.gov/pubmed/28117367
http://dx.doi.org/10.1038/srep41248