Production of functional human nerve growth factor from the saliva of transgenic mice by using salivary glands as bioreactors

The salivary glands of animals have great potential to act as powerful bioreactors to produce human therapeutic proteins. Human nerve growth factor (hNGF) is an important pharmaceutical protein that is clinically effective in the treatment of many human neuronal and non-neuronal diseases. In this st...

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Detalles Bibliográficos
Autores principales: Zeng, Fang, Li, Zicong, Zhu, Qingchun, Dong, Rui, Zhao, Chengcheng, Li, Guoling, Li, Guo, Gao, Wenchao, Jiang, Gelong, Zheng, Enqin, Cai, Gengyuan, Moisyadi, Stefan, Urschitz, Johann, Yang, Huaqiang, Liu, Dewu, Wu, Zhenfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259756/
https://www.ncbi.nlm.nih.gov/pubmed/28117418
http://dx.doi.org/10.1038/srep41270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259756/
https://www.ncbi.nlm.nih.gov/pubmed/28117418
http://dx.doi.org/10.1038/srep41270

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