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Males develop faster and more severe hepatocellular carcinoma than females in kras(V12) transgenic zebrafish

Hepatocellular carcinoma (HCC) is more prevalent in men than women, but the reason for this gender disparity is not well understood. To investigate whether zebrafish could be used to study the gender disparity of HCC, we compared the difference of liver tumorigenesis between female and male fish dur...

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Detalles Bibliográficos
Autores principales: Li, Yan, Li, Hankun, Spitsbergen, Jan M., Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259773/
https://www.ncbi.nlm.nih.gov/pubmed/28117409
http://dx.doi.org/10.1038/srep41280