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Piperine regulates UCP1 through the AMPK pathway by generating intracellular lactate production in muscle cells

This study characterizes the human metabolic response to piperine, a curcumin extract, and the details of its underlying molecular mechanism. Using (1)H-NMR-based metabolome analysis, we showed the metabolic effect of piperine on skeletal muscle and found that piperine increased the level of intrace...

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Detalles Bibliográficos
Autores principales: Kim, Nami, Nam, Miso, Kang, Mi Sun, Lee, Jung Ok, Lee, Yong Woo, Hwang, Geum-Sook, Kim, Hyeon Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259784/
https://www.ncbi.nlm.nih.gov/pubmed/28117414
http://dx.doi.org/10.1038/srep41066