Calcium-independent disruption of microtubule dynamics by nanosecond pulsed electric fields in U87 human glioblastoma cells

High powered, nanosecond duration, pulsed electric fields (nsPEF) cause cell death by a mechanism that is not fully understood and have been proposed as a targeted cancer therapy. Numerous chemotherapeutics work by disrupting microtubules. As microtubules are affected by electrical fields, this stud...

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Detalles Bibliográficos
Autores principales: Carr, Lynn, Bardet, Sylvia M., Burke, Ryan C., Arnaud-Cormos, Delia, Leveque, Philippe, O’Connor, Rodney P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259788/
https://www.ncbi.nlm.nih.gov/pubmed/28117459
http://dx.doi.org/10.1038/srep41267

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