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Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis

The small heterodimer partner (SHP) is an orphan nuclear receptor that lacks the DNA binding domain while conserves a putative ligand-binding site, thought that endogenous ligands for this receptor are unknown. Previous studies have determined that SHP activation protects against development of live...

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Detalles Bibliográficos
Autores principales: Cipriani, Sabrina, Carino, Adriana, Masullo, Dario, Zampella, Angela, Distrutti, Eleonora, Fiorucci, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259793/
https://www.ncbi.nlm.nih.gov/pubmed/28117422
http://dx.doi.org/10.1038/srep41055