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Prediction of HIV-1 protease cleavage site using a combination of sequence, structural, and physicochemical features

BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) aspartic protease is an important enzyme owing to its imperative part in viral development and a causative agent of deadliest disease known as acquired immune deficiency syndrome (AIDS). Development of HIV-1 protease inhibitors can help und...

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Detalles Bibliográficos
Autores principales: Singh, Onkar, Su, Emily Chia-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259813/
https://www.ncbi.nlm.nih.gov/pubmed/28155640
http://dx.doi.org/10.1186/s12859-016-1337-6