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Prediction of HIV-1 protease cleavage site using a combination of sequence, structural, and physicochemical features
BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) aspartic protease is an important enzyme owing to its imperative part in viral development and a causative agent of deadliest disease known as acquired immune deficiency syndrome (AIDS). Development of HIV-1 protease inhibitors can help und...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259813/ https://www.ncbi.nlm.nih.gov/pubmed/28155640 http://dx.doi.org/10.1186/s12859-016-1337-6 |