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Evaluating the effect of database inflation in proteogenomic search on sensitive and reliable peptide identification
BACKGROUND: Proteogenomics is a promising approach for various tasks ranging from gene annotation to cancer research. Databases for proteogenomic searches are often constructed by adding peptide sequences inferred from genomic or transcriptomic evidence to reference protein sequences. Such inflation...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259817/ https://www.ncbi.nlm.nih.gov/pubmed/28155652 http://dx.doi.org/10.1186/s12864-016-3327-5 |