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Evaluating the effect of database inflation in proteogenomic search on sensitive and reliable peptide identification

BACKGROUND: Proteogenomics is a promising approach for various tasks ranging from gene annotation to cancer research. Databases for proteogenomic searches are often constructed by adding peptide sequences inferred from genomic or transcriptomic evidence to reference protein sequences. Such inflation...

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Detalles Bibliográficos
Autores principales: Li, Honglan, Joh, Yoon Sung, Kim, Hyunwoo, Paek, Eunok, Lee, Sang-Won, Hwang, Kyu-Baek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259817/
https://www.ncbi.nlm.nih.gov/pubmed/28155652
http://dx.doi.org/10.1186/s12864-016-3327-5