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Predicting MoRFs in protein sequences using HMM profiles
BACKGROUND: Intrinsically Disordered Proteins (IDPs) lack an ordered three-dimensional structure and are enriched in various biological processes. The Molecular Recognition Features (MoRFs) are functional regions within IDPs that undergo a disorder-to-order transition on binding to a partner protein...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259822/ https://www.ncbi.nlm.nih.gov/pubmed/28155710 http://dx.doi.org/10.1186/s12859-016-1375-0 |