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Prioritizing biological pathways by recognizing context in time-series gene expression data

BACKGROUND: The primary goal of pathway analysis using transcriptome data is to find significantly perturbed pathways. However, pathway analysis is not always successful in identifying pathways that are truly relevant to the context under study. A major reason for this difficulty is that a single ge...

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Detalles Bibliográficos
Autores principales: Lee, Jusang, Jo, Kyuri, Lee, Sunwon, Kang, Jaewoo, Kim, Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259824/
https://www.ncbi.nlm.nih.gov/pubmed/28155707
http://dx.doi.org/10.1186/s12859-016-1335-8