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LNDriver: identifying driver genes by integrating mutation and expression data based on gene-gene interaction network

BACKGROUND: Cancer is a complex disease which is characterized by the accumulation of genetic alterations during the patient’s lifetime. With the development of the next-generation sequencing technology, multiple omics data, such as cancer genomic, epigenomic and transcriptomic data etc., can be mea...

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Detalles Bibliográficos
Autores principales: Wei, Pi-Jing, Zhang, Di, Xia, Junfeng, Zheng, Chun-Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259866/
https://www.ncbi.nlm.nih.gov/pubmed/28155630
http://dx.doi.org/10.1186/s12859-016-1332-y