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LNDriver: identifying driver genes by integrating mutation and expression data based on gene-gene interaction network
BACKGROUND: Cancer is a complex disease which is characterized by the accumulation of genetic alterations during the patient’s lifetime. With the development of the next-generation sequencing technology, multiple omics data, such as cancer genomic, epigenomic and transcriptomic data etc., can be mea...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259866/ https://www.ncbi.nlm.nih.gov/pubmed/28155630 http://dx.doi.org/10.1186/s12859-016-1332-y |