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Expression of cellular protective proteins SIRT1, HSP70 and SOD2 correlates with age and is significantly higher in NK cells of the oldest seniors

BACKGROUND: NK cells are key effector lymphocytes of innate immunity provided with constitutive cytolytic activity, however, their role in human ageing is not entirely understood. The study aimed to analyze the expression of proteins involved in cellular stress response sirtuin 1 (SIRT1), heat shock...

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Detalles Bibliográficos
Autores principales: Kaszubowska, Lucyna, Foerster, Jerzy, Kaczor, Jan Jacek, Schetz, Daria, Ślebioda, Tomasz Jerzy, Kmieć, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259875/
https://www.ncbi.nlm.nih.gov/pubmed/28127381
http://dx.doi.org/10.1186/s12979-017-0085-4