Subtype-specific CpG island shore methylation and mutation patterns in 30 breast cancer cell lines

BACKGROUND: Aberrant epigenetic modifications, including DNA methylation, are key regulators of gene activity in tumorigenesis. Breast cancer is a heterogeneous disease, and large-scale analyses indicate that tumor from normal and benign tissues, as well as molecular subtypes of breast cancer, can b...

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Detalles Bibliográficos
Autores principales: Chae, Heejoon, Lee, Sangseon, Nephew, Kenneth P., Kim, Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259919/
https://www.ncbi.nlm.nih.gov/pubmed/28155687
http://dx.doi.org/10.1186/s12918-016-0356-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259919/
https://www.ncbi.nlm.nih.gov/pubmed/28155687
http://dx.doi.org/10.1186/s12918-016-0356-2

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