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Structural analyses of 2015-updated drug-resistant mutations in HIV-1 protease: an implication of protease inhibitor cross-resistance

BACKGROUND: Strategies to control HIV for improving the quality of patient lives have been aided by the Highly Active Anti-Retroviral Therapy (HAART), which consists of a cocktail of inhibitors targeting key viral enzymes. Numerous new drugs have been developed over the past few decades but viral re...

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Detalles Bibliográficos
Autores principales: Su, Chinh Tran-To, Ling, Wei-Li, Lua, Wai-Heng, Haw, Yu-Xuan, Gan, Samuel Ken-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259968/
https://www.ncbi.nlm.nih.gov/pubmed/28155724
http://dx.doi.org/10.1186/s12859-016-1372-3