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Decreased expression of miR-939 contributes to chemoresistance and metastasis of gastric cancer via dysregulation of SLC34A2 and Raf/MEK/ERK pathway

BACKGROUND: The development of chemoresistance and metastasis are the leading causes of death for gastric cancer (GC) patients, however, the molecular mechanisms involved remain unclear. Dysregulation of miRNAs is associated with a variety of disease, including GC. Recently, microarray profiling ana...

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Detalles Bibliográficos
Autores principales: Zhang, Jia-Xing, Xu, Yi, Gao, Ying, Chen, Cui, Zheng, Zhou-San, Yun, Miao, Weng, Hui-Wen, Xie, Dan, Ye, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259972/
https://www.ncbi.nlm.nih.gov/pubmed/28114937
http://dx.doi.org/10.1186/s12943-017-0586-y