Joining the in vitro immunization of alpaca lymphocytes and phage display: rapid and cost effective pipeline for sdAb synthesis

BACKGROUND: Camelids possess unique functional heavy chain antibodies, which can be produced and modified in vitro as a single domain antibody (sdAb or nanobody) with full antigen binding ability. Production of sdAb in conventional manner requires active immunization of Camelidae animal, which is la...

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Detalles Bibliográficos
Autores principales: Comor, Lubos, Dolinska, Saskia, Bhide, Katarina, Pulzova, Lucia, Jiménez-Munguía, Irene, Bencurova, Elena, Flachbartova, Zuzana, Potocnakova, Lenka, Kanova, Evelina, Bhide, Mangesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259998/
https://www.ncbi.nlm.nih.gov/pubmed/28114943
http://dx.doi.org/10.1186/s12934-017-0630-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259998/
https://www.ncbi.nlm.nih.gov/pubmed/28114943
http://dx.doi.org/10.1186/s12934-017-0630-z

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