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Permeability across a novel microfluidic blood-tumor barrier model

BACKGROUND: The lack of translatable in vitro blood-tumor barrier (BTB) models creates challenges in the development of drugs to treat tumors of the CNS and our understanding of how the vascular changes at the BBB in the presence of a tumor. METHODS: In this study, we characterize a novel microfluid...

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Detalles Bibliográficos
Autores principales: Terrell-Hall, Tori B., Ammer, Amanda G., Griffith, Jessica I. G., Lockman, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260004/
https://www.ncbi.nlm.nih.gov/pubmed/28114946
http://dx.doi.org/10.1186/s12987-017-0050-9