Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation

BACKGROUND: Oxidative stress is recognized to be one of predisposing factor in the pathogenesis of COPD. The oxidant/antioxidant imbalance is significantly pronounced in patients with COPD exacerbation. N-acetylcysteine (NAC) seems to be able to reduce COPD exacerbations by modulating the oxidative...

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Detalles Bibliográficos
Autores principales: Cazzola, Mario, Calzetta, Luigino, Facciolo, Francesco, Rogliani, Paola, Matera, Maria Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260037/
https://www.ncbi.nlm.nih.gov/pubmed/28118826
http://dx.doi.org/10.1186/s12931-016-0500-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260037/
https://www.ncbi.nlm.nih.gov/pubmed/28118826
http://dx.doi.org/10.1186/s12931-016-0500-y

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