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Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation
BACKGROUND: Oxidative stress is recognized to be one of predisposing factor in the pathogenesis of COPD. The oxidant/antioxidant imbalance is significantly pronounced in patients with COPD exacerbation. N-acetylcysteine (NAC) seems to be able to reduce COPD exacerbations by modulating the oxidative...
Autores principales: | Cazzola, Mario, Calzetta, Luigino, Facciolo, Francesco, Rogliani, Paola, Matera, Maria Gabriella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260037/ https://www.ncbi.nlm.nih.gov/pubmed/28118826 http://dx.doi.org/10.1186/s12931-016-0500-y |
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