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The extraction of drug-disease correlations based on module distance in incomplete human interactome

BACKGROUND: Extracting drug-disease correlations is crucial in unveiling disease mechanisms, as well as discovering new indications of available drugs, or drug repositioning. Both the interactome and the knowledge of disease-associated and drug-associated genes remain incomplete. RESULTS: We present...

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Detalles Bibliográficos
Autores principales: Yu, Liang, Wang, Bingbo, Ma, Xiaoke, Gao, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260043/
https://www.ncbi.nlm.nih.gov/pubmed/28155709
http://dx.doi.org/10.1186/s12918-016-0364-2