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Th17-skewed immune response and cluster of differentiation 40 ligand expression in canine steroid-responsive meningitis-arteritis, a large animal model for neutrophilic meningitis

BACKGROUND: Steroid-responsive meningitis-arteritis (SRMA) is an immune-mediated disorder characterized by neutrophilic pleocytosis and an arteritis particularly in the cervical leptomeninges. Previous studies of the disease have shown increased levels of IL-6 and TGF-ß(1) in cerebrospinal fluid (CS...

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Detalles Bibliográficos
Autores principales: Freundt-Revilla, Jessica, Maiolini, Arianna, Carlson, Regina, Beyerbach, Martin, Rentmeister, Kai, Flegel, Thomas, Fischer, Andrea, Tipold, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260073/
https://www.ncbi.nlm.nih.gov/pubmed/28114998
http://dx.doi.org/10.1186/s12974-016-0784-3