Exploiting the recognition code for elucidating the mechanism of zinc finger protein-DNA interactions

BACKGROUND: Engineering zinc finger protein motifs for specific binding to double-stranded DNA is critical for targeted genome editing. Most existing tools for predicting DNA-binding specificity in zinc fingers are trained on data obtained from naturally occurring proteins, thereby skewing the predi...

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Detalles Bibliográficos
Autores principales: Dutta, Shayoni, Madan, Spandan, Sundar, Durai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260074/
https://www.ncbi.nlm.nih.gov/pubmed/28155654
http://dx.doi.org/10.1186/s12864-016-3324-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260074/
https://www.ncbi.nlm.nih.gov/pubmed/28155654
http://dx.doi.org/10.1186/s12864-016-3324-8

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