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Mechanical regulation of calcium signaling of HL-60 on P-selectin under flow

BACKGROUND: Binding of P-selectin to P-selectin glycoprotein ligand-1 (PSGL-1) makes neutrophils roll on and adhere to inflammatory site. Intracellular calcium bursting of adhered neutrophils is a key event for subsequent arresting firmly at and migrating into the injured tissue. But, it remains unc...

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Detalles Bibliográficos
Autores principales: Huang, Bing, Ling, Yingchen, Lin, Jiangguo, Fang, Ying, Wu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260098/
https://www.ncbi.nlm.nih.gov/pubmed/28155729
http://dx.doi.org/10.1186/s12938-016-0271-1