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Grouping miRNAs of similar functions via weighted information content of gene ontology

BACKGROUND: Regulation mechanisms between miRNAs and genes are complicated. To accomplish a biological function, a miRNA may regulate multiple target genes, and similarly a target gene may be regulated by multiple miRNAs. Wet-lab knowledge of co-regulating miRNAs is limited. This work introduces a c...

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Detalles Bibliográficos
Autores principales: Lan, Chaowang, Chen, Qingfeng, Li, Jinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260111/
https://www.ncbi.nlm.nih.gov/pubmed/28155659
http://dx.doi.org/10.1186/s12859-016-1367-0