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Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death
Proper regulation of cell death signaling is crucial for the maintenance of homeostasis and prevention of disease. A caspase-independent regulated form of cell death called necroptosis is rapidly emerging as an important mediator of a number of human pathologies including inflammatory bowel disease...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260504/ https://www.ncbi.nlm.nih.gov/pubmed/27518435 http://dx.doi.org/10.1038/cdd.2016.78 |