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CDK1-PDK1-PI3K/Akt signaling pathway regulates embryonic and induced pluripotency
The mechanisms of how signaling pathways are coordinated and integrated for the maintenance of the self-renewal of human embryonic stem cells (hESCs) and the acquisition of pluripotency in reprogramming are still only partly understood. CDK1 is a key regulator of mitosis. Recently, CDK1 has been sho...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260505/ https://www.ncbi.nlm.nih.gov/pubmed/27636107 http://dx.doi.org/10.1038/cdd.2016.84 |