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LH prevents cisplatin-induced apoptosis in oocytes and preserves female fertility in mouse

Premature ovarian failure and female infertility are frequent side effects of anticancer therapies, owing to the extreme sensitivity of the ovarian reserve oocytes to the damaging effects of irradiation and chemotherapy on DNA. We report here a robust protective effect of luteinizing hormone (LH) on...

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Detalles Bibliográficos
Autores principales: Rossi, Valerio, Lispi, Monica, Longobardi, Salvatore, Mattei, Maurizio, Rella, Francesca Di, Salustri, Antonietta, De Felici, Massimo, Klinger, Francesca G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260508/
https://www.ncbi.nlm.nih.gov/pubmed/27689876
http://dx.doi.org/10.1038/cdd.2016.97