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Rules of co-occurring mutations characterize the antigenic evolution of human influenza A/H3N2, A/H1N1 and B viruses

BACKGROUND: The human influenza viruses undergo rapid evolution (especially in hemagglutinin (HA), a glycoprotein on the surface of the virus), which enables the virus population to constantly evade the human immune system. Therefore, the vaccine has to be updated every year to stay effective. There...

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Detalles Bibliográficos
Autores principales: Chen, Haifen, Zhou, Xinrui, Zheng, Jie, Kwoh, Chee-Keong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260787/
https://www.ncbi.nlm.nih.gov/pubmed/28117657
http://dx.doi.org/10.1186/s12920-016-0230-5